Allorecognition Unveiled: Integrating Recent Breakthroughs Into the Current Paradigm [PDF]
Transplant InternationalIn transplantation, genetic differences between donor and recipient trigger immune responses that cause graft rejection. Allorecognition, the process by which the immune system discriminates allogeneic grafts, targets major histocompatibility complex ...
Xavier Charmetant +6 more
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Creation and Maintenance of Variation in Allorecognition Loci [PDF]
Frontiers in Immunology, 2011 Allorecognition is the ability of an organism to differentiate self or close relatives from unrelated individuals. Effective allorecognition systems are critical to the survival of organisms; they prevent inbreeding, protect against pathogens, and ...
Anthony W De Tomaso, Tony de Tomaso
exaly +4 more sources
TgrC1 Has Distinct Functions in Dictyostelium Development and Allorecognition. [PDF]
PLoS ONE, 2015 The cell adhesion glycoproteins, TgrB1 and TgrC1, are essential for Dictyostelium development and allorecognition, but it has been impossible to determine whether their pleiotropic roles are due to one common function or to distinct functions in separate
Yue Wang, Gad Shaulsky
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A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in Neurospora crassa allorecognition [PDF]
eLife, 2022 Organisms require the ability to differentiate themselves from organisms of different or even the same species. Allorecognition processes in filamentous fungi are essential to ensure identity of an interconnected syncytial colony to protect it from ...
Tyler C Detomasi +5 more
doaj +2 more sources
Population Genetics of the Emergence and Evolution of Allogenic Recognition During Fertilization [PDF]
BiomoleculesAllorecognition, or distinguishing between the self and nonself within the same species, is observed in both animals and plants, particularly in the context of immune reactions and self-incompatibility in sexual reproduction.
Masahiro Naruse +2 more
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Allorecognition triggers autophagy and subsequent necrosis in the cnidarian Hydractinia symbiolongicarpus. [PDF]
PLoS ONE, 2012 Transitory fusion is an allorecognition phenotype displayed by the colonial hydroid Hydractinia symbiolongicarpus when interacting colonies share some, but not all, loci within the allorecognition gene complex (ARC).
Leo W Buss +6 more
doaj +2 more sources
Regulated cell death and DAMPs as biomarkers and therapeutic targets in normothermic perfusion of transplant organs. Part 2: implementation strategies [PDF]
Frontiers in TransplantationThis Part 2 of a bipartite review commences with the delineation of a conceptual model outlining the fundamental role of injury-induced regulated cell death (RCD) in the release of DAMPs that drive innate immune responses involved in early inflammation ...
Walter G. Land +5 more
doaj +2 more sources
From seabed to sickbed: lessons gained from allorecognition in marine invertebrates [PDF]
Frontiers in ImmunologyDespite decades of progress, long-term outcomes in human organ transplantation remain challenging. Functional decline in transplanted organs has stagnated over the past two decades, with most patients requiring lifelong immunosuppression, therapies that ...
Baruch Rinkevich
doaj +2 more sources
Exceptional Diversity of Allorecognition Receptors in a Nonvertebrate Chordate Reveals Principles of Innate Allelic Discrimination [PDF]
Proceedings of the National Academy of Sciences of the United States of AmericaAnthony W De Tomaso +2 more
exaly +2 more sources
Establishment of the immunological self in juvenile Patiria pectinifera post-metamorphosis
Frontiers in Immunology, 2022 Ontogeny of the immune system is a fundamental immunology issue. One indicator of immune system maturation is the establishment of the immunological self, which describes the ability of the immune system to distinguish allogeneic individuals ...
Mizuki Taguchi +3 more
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