Results 21 to 30 of about 3,437 (186)
Until recently, the vigorous T cell response via the direct pathway has overshadowed studies involving the indirect pathway. Thus, while the direct pathway has previously been considered to be the main driving force in alloimmune responses, there is an increasing body of data to support a prominent role of the indirect pathway in transplant rejection ...
I, Côté, N J, Rogers, R I, Lechler
+7 more sources
Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria
Previously, we have demonstrated that the transplantation of autologous mitochondria is cardioprotective. No immune or autoimmune response was detectable following the single injection of autologous mitochondria. To expand the therapeutic potential and safety of mitochondrial transplantation, we now investigate the immune response to single and serial ...
Ramirez-Barbieri, Giovanna +10 more
openaire +3 more sources
SummaryVertebrates mount strong adaptive immune responses to transplanted organs (allografts), but the mechanisms by which the innate immune system initiates this response are not completely understood. In anti‐microbial immunity, non‐self molecules associated with pathogens but not present in the host induce the maturation of innate antigen‐presenting
Martin H, Oberbarnscheidt +1 more
openaire +2 more sources
Genesis of a fungal non-self recognition repertoire. [PDF]
Conspecific allorecognition, the ability for an organism to discriminate its own cells from those of another individual of the same species, has been developed by many organisms.
Mathieu Paoletti +2 more
doaj +1 more source
How does a protein at the cell wall determine if a newly encountered fungus is safe to fuse with?
Magnus Hallas-Møller, Katja S Johansen
doaj +1 more source
Cytoplasmic Mixing, Not Nuclear Coexistence, Can Explain Somatic Incompatibility in Basidiomycetes
Nonself recognition leading to somatic incompatibility (SI) is commonly used by mycologists to distinguish fungal individuals. Despite this, the process remains poorly understood in basidiomycetes as all current models of SI are based on genetic and ...
Ben Auxier +5 more
doaj +1 more source
Selection against somatic parasitism can maintain allorecognition in fungi [PDF]
Fusion between multicellular individuals is possible in many organisms with modular, indeterminate growth, such as marine invertebrates and fungi.
Aanen, D.K. +5 more
core +2 more sources
Expression of putative immune response genes during early ontogeny in the coral Acropora millepora. [PDF]
Corals, like many other marine invertebrates, lack a mature allorecognition system in early life history stages. Indeed, in early ontogeny, when corals acquire and establish associations with various surface microbiota and dinoflagellate endosymbionts ...
Eneour Puill-Stephan +4 more
doaj +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source

