Results 31 to 40 of about 3,437 (186)

Allorecognition and the spectrum of kidney transplant rejection [PDF]

open access: yes, 2022
Detection of mismatched human leukocyte antigens by adaptive immune cells is considered as the main cause of transplant rejection, leading to either T-cell mediated rejection or antibody-mediated rejection.
Koenig, Alice   +11 more
core   +1 more source

Synergies of Extracellular Vesicles and Microchimerism in Promoting Immunotolerance During Pregnancy

open access: yesFrontiers in Immunology, 2022
The concept of biological identity has been traditionally a central issue in immunology. The assumption that entities foreign to a specific organism should be rejected by its immune system, while self-entities do not trigger an immune response is ...
José M. Murrieta-Coxca   +4 more
doaj   +1 more source

Invertebrate allorecognition [PDF]

open access: yesCurrent Biology, 2019
Most colonial marine invertebrates live as surface encrustations in benthic environments. As they grow, these animals frequently encounter other members of their own species. These encounters typically lead to conflict, in which the colonies aggressively compete for space, or co-existence, in which the colonies peacefully border each other.
openaire   +2 more sources

Model Systems of Invertebrate Allorecognition [PDF]

open access: yesCurrent Biology, 2011
Nearly all colonial marine invertebrates are capable of allorecognition--the ability to distinguish between self and genetically distinct members of the same species. When two or more colonies grow into contact, they either reject each other and compete for the contested space or fuse and form a single, chimeric colony. The specificity of this response
Rosengarten, Rafael D.   +1 more
openaire   +2 more sources

Cyclic AMP is dispensable for allorecognition in Dictyostelium cells overexpressing PKA-C [PDF]

open access: yes, 2021
Allorecognition and tissue formation are interconnected processes that require signaling between matching pairs of the polymorphic transmembrane proteins TgrB1 and TgrC1 in Dictyostelium.
Hirose, Shigenori   +5 more
core   +1 more source

Botryllus schlosseri as a Unique Colonial Chordate Model for the Study and Modulation of Innate Immune Activity

open access: yesMarine Drugs, 2021
Understanding the mechanisms that sustain immunological nonreactivity is essential for maintaining tissue in syngeneic and allogeneic settings, such as transplantation and pregnancy tolerance.
Oron Goldstein   +7 more
doaj   +1 more source

Invertebrate Allorecognition: The Origins of Histocompatibility [PDF]

open access: yesCurrent Biology, 2009
Alloimmune specificity and histocompatibility, driven by genetic polymorphism, are ancient determinants of self-/non-self-recognition. Recent molecular genetic evidence has revealed an allodeterminant in the cnidarian Hydractinia that consistently predicts histocompatibility reactions.
Dishaw, Larry J., Litman, Gary W.
openaire   +2 more sources

Identification of allorecognition loci in neurospora crassa by genomics and evolutionary approaches [PDF]

open access: yes, 2015
Understanding the genetic and molecular bases of the ability to distinguish self from nonself (allorecognition) and mechanisms underlying evolution of allorecognition systems is an important endeavor for understanding cases where it becomes dysfunctional,
Hutchison, Elizabeth
core   +3 more sources

The Fetal Allograft Revisited: Does the Study of an Ancient Invertebrate Species Shed Light on the Role of Natural Killer Cells at the Maternal-Fetal Interface?

open access: yesClinical and Developmental Immunology, 2008
Human pregnancy poses a fundamental immunological problem because the placenta and fetus are genetically different from the host mother. Classical transplantation theory has not provided a plausible solution to this problem.
Amy Lightner   +3 more
doaj   +1 more source

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