Results 111 to 120 of about 11,850,269 (338)
, 2012 Ferromanganese nodule fields and hardgrounds have recently been discovered in the Cadiz Contourite Channel in the Gulf of Cadiz (850–1000 m). This channel is part of a large contourite depositional system generated by the Mediterranean Outflow Water ...
F. González +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Modelling of the Present Oceanographic Situation of the Gulfs of Patras and Corinth
Journal of Marine Science and EngineeringIn our study we investigated the hydrodynamic circulation of the Gulfs of Patras and Corinth through modelling. To this end, ROMS was used to numerically calculate the parameters of the waters for these peculiar semi-enclosed basins.
Basile Caterina +3 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Journal of Marine Science and EngineeringBottom trawling in submarine canyons can affect their sedimentary dynamics, but studies addressing this topic are still scarce. In the Gulf of Palermo (NW Sicily, SW Mediterranean Sea), bottom trawling occurs on the continental slope, but principally ...
Marta Arjona-Camas +4 more
doaj +1 more source
Open-flavor charmed/bottom $sq\bar q\bar Q$ and $qq\bar q\bar Q$ tetraquark states
, 2017 We provide comprehensive investigations for the mass spectrum of exotic open-flavor charmed/bottom $sq\bar q\bar c$, $qq\bar q\bar c$, $sq\bar q\bar b$, $qq\bar q\bar b$ tetraquark states with various spin-parity assignments $J^P=0^+, 1^+, 2^+$ and $0^-,
Chen, Hua-Xing +4 more
core +2 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Acoustic tracking of woodhead seabed drifters [PDF]
An investigation was conducted to determine the feasibility of tracking Woodhead seabed drifters that were instrumented with miniature acoustic transmitters having a range in water in excess of 1.0 n.mi.
Lovelady, R. W., Mayhue, R. J.
core +1 more source