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Botulinum Toxins

2020
Clostridium botulinum is an anaerobic, gram-positive bacterium that secretes an extremely large neurotoxic molecule (900 kDa), which produces food poisoning or botulism. It is now also used in medicine to treat diseases according to Paracelsus's paradigm that the difference between a poison and a drug lies in the dose.
Signorini, Massimo   +5 more
openaire   +2 more sources

Botulinum Toxin

Critical Care Clinics, 2005
Botulinum toxin is regarded as the most lethal substance known. It is estimated that the human LD50 for inhalation botulism is 1 to 3 nanograms of toxin/kilogram body mass. Although only three cases of inhalational botulism have been described, an understanding of the pathophysiology of food-borne outbreaks, wound botulism, and infant botulism, and ...
openaire   +2 more sources

Update on Botulinum Toxin

Seminars in Cutaneous Medicine and Surgery, 2006
Botulinum toxin for facial enhancement is currently the most popular aesthetic procedure performed in the United States. New developments have occurred within the last few years. Patients prefer having multiple areas of the upper face treated which increases patient satisfaction.
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Botulinum Toxin A

2012
There is a trend toward greater use of cosmetic procedures by ethnic minorities. The greatest level of increased interest is among Latino and African American patients, with Latino patients leading all minority groups in the number of cosmetic procedures performed in 2008.
Carlos A. Charles, Elena Jones
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Topical botulinum toxin

2016
Nanotechnology is a rapidly growing discipline that capitalizes on the unique properties of matter engineered on the nanoscale. Vehicles incorporating nanotechnology have led to great strides in drug delivery, allowing for increased active ingredient stability, bioavailability, and site-specific targeting. Botulinum toxin has historically been used for
Ashley Collins, Adnan Nasir
openaire   +3 more sources

Botulinum Toxin for Rhinitis

Current Allergy and Asthma Reports, 2016
Rhinitis is a common clinical entity. Besides nasal obstruction, itching, and sneezing, one of the most important symptoms of rhinitis is nasal hypersecretion produced by nasal glands and exudate from the nasal vascular bed. Allergic rhinitis is an IgE-mediated inflammatory reaction of nasal mucosa after exposure to environmental allergens.
Cengiz Özcan, Onur Ismi
openaire   +3 more sources

Botulinum Toxin A

2001
Bereits der Name Botulinum Toxin A verrat viel uber die Historie einer Substanz, die in den letzten Jahren eine sprunghafte Karriere vom Gift zum Arzneimittel erfahren hat. Bekannt geworden ist das Toxin als Verursacher des Botulismus, einer Lebensmittelvergiftung, die durch verdorbene Wurst- und Konservenwaren (Botulus lat.
Mall, Volker   +4 more
openaire   +3 more sources

Pharmacology of botulinum toxin

Journal of the American Academy of Dermatology, 2000
Botulinum toxin has a well-defined role among dermatologists for the treatment of facial wrinkling, brow position, and palmar and axillary hyperhidrosis.The purpose of this study is to educate dermatologists on the pharmacology of botulinum toxin.A retrospective review of the literature on botulinum toxin from 1962 to the present was conducted.
Wilber Huang   +2 more
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Botulinum Toxin and Pain

2020
This chapter is focused on analgesic mechanism of action of botulinum toxin type A (BoNT-A) including the action beyond peripheral nerve endings. With the exception of the meninges and possibly urinary bladder, the presence of BoNT-A activity in the periphery, cleaving SNAP25 as a target molecule, up to now was not convincingly shown.
openaire   +3 more sources

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