Results 51 to 60 of about 943,757 (267)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Precession of timelike bound orbits in Kerr spacetime
European Physical Journal C: Particles and Fields, 2021 Astrometric observations of S-stars provide a unique opportunity to probe the nature of Sagittarius-A* (Sgr-A*). In view of this, it has become important to understand the nature and behavior of timelike bound trajectories of particles around a massive ...
Parth Bambhaniya +5 more
doaj +1 more source
Causal relationship between income inequality and economic growth in Ethiopia
Cogent Economics & Finance, 2022 The aim of this study was to see the direction of causality and to investigate the existence of a long-run relationship between income inequality and economic growth in Ethiopia.
Mihret Wolde +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Hong Kong Physiotherapy Journal, 2015 Background: High-level mobility (HLM) training including running forms an integral part of physical rehabilitation for neurologically impaired patients.
Marek Gorski, Master of Education (Physical Education) +2 more
doaj +1 more source
Journal of Applied Economics, 2023 This research examines the linkages between trade, financial openness, and economic growth in China from 1992 to 2021, using Granger causality analysis in the ECM model to identify the trend of a causal relationship between the variables.
Khalid Usman
doaj +1 more source
Sharp Bounds for Generalized Uniformity Testing
CoRR, 2017 We study the problem of generalized uniformity testing \cite{BC17} of a discrete probability distribution: Given samples from a probability distribution $p$ over an {\em unknown} discrete domain $\mathbfΩ$, we want to distinguish, with probability at least $2/3$, between the case that $p$ is uniform on some {\em subset} of $\mathbfΩ$ versus $ε$-far, in
Diakonikolas, Ilias +2 more
openaire +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Complexity bounds for zero-test algorithms
Journal of Symbolic Computation, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Joris van der Hoeven, John Shackell
openaire +2 more sources
Lower Bounds for Testing Function Isomorphism [PDF]
2010 IEEE 25th Annual Conference on Computational Complexity, 2010 We prove new lower bounds in the area of property testing of boolean functions. Specifically, we study the problem of testing whether a boolean function f is isomorphic to a fixed function g (i.e., is equal to g up to permutation of the input variables). The analogous problem for testing graphs was solved by Fischer in 2005.
Eric Blais, Ryan O'Donnell
openaire +1 more source