Results 101 to 110 of about 1,466,559 (292)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

An Algebraic Theory Of Boundary Crossing Transitions

open access: yesElectronic Notes in Theoretical Computer Science, 2005
AbstractThis paper gives a process-algebraic semantics for the hierarchical state machine (HSM) fragment of Statecharts, in which state transitions are permitted to cross state boundaries. Although frowned upon by researchers as promoting unstructured modeling, such transitions are used extensively in practice to model parameterized start states and ...
Arnab Ray, Rance Cleaveland, Arne Skou
openaire   +3 more sources

Translanguaging as Boundary Crossing

open access: yes, 2023
Objectives: 1. Determine attitudes towards translanguaging in the Netherlands; 2. Investigate interactions between non-formal and informal learning settings and the role of translanguaging strategies therein; 3.
Hanneke Baart   +6 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Navigating towards interdisciplinarity: a grounded theory exploration of a collaborative SoTL boundary experience

open access: yesCogent Education
This study investigates the intricacies of interdisciplinary collaboration within the Scholarship of Teaching and Learning (SoTL), a field characterized by its epistemic and methodological diversity.
Janice Miller-Young   +2 more
doaj   +1 more source

Boundary Crossing Issues Between Academia, Business and Government [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2005
In this paper issues arising from crossing boundaries between the three worlds of academia, business and government in performing informatics research are explored.
Kay Fielden
doaj  

Learning in and across communities of practice: health professions education students' learning from boundary crossing. [PDF]

open access: yesAdv Health Sci Educ Theory Pract, 2022
Stoffels M   +5 more
europepmc   +1 more source

The Gray Areas of Boundary Crossings and Violations [PDF]

open access: yesAmerican Journal of Psychotherapy, 2003
The term "boundary violation" has become synonymous with unethical practice in psychotherapy, prompting a "black-or-white" view among clinicians and boards of review. But the current conceptual ambiguity about boundary interventions subjects clinicians to after-the-fact second-guessing that can be professionally ruinous at worst and may contribute to ...
openaire   +2 more sources

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