Results 91 to 100 of about 1,466,559 (292)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Crossing the Boundary: From Experimental Psychology to Ethnomusicology
In attempting to understand the difficulties raised by Judith Becker’s experiences with crossing boundaries between disciplines, the author is prompted to examine how he successfully negotiated the intellectual journey from psychology to musicology in ...
John Baily
doaj +1 more source
On boundary crossing probabilities for diffusion processes
In this paper, we establish a relationship between the asymptotic form of conditional boundary crossing probabilities and first passage time densities for diffusion processes. Namely, we show that, under broad assumptions, the first crossing time density of a general curvilinear boundary by a general time-homogeneous diffusion process has a product ...
Borovkov, K., Downes, A.N.
openaire +3 more sources
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
In her paper “Crossing Boundaries”, Judith Becker raises and discusses important points about where various boundaries between different ways of studying music might lie, how we negotiate those boundaries, and some of the frustrations that ensue in ...
Eric Clarke
doaj +1 more source
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Crossing the Boundary into the Russian “Imagined Community”. “Language”, “Culture” and “Religion” in Russian Media Discourse on the Integration of Immigrants Jussi Lassila reviews Christine Myrdahl Lukash’ doctoral dissertation Crossing the Boundary into
Jussi Lassila
doaj +1 more source
Searching for the Good Life: Boundary Crossing, Co-Existence, and Conviviality. [PDF]
Coeckelbergh M, Reader J.
europepmc +1 more source
Asymptotic Expansions in Boundary Crossing Problems
Let \(X_ 1,X_ 2,..\). be i.i.d. with mean \(\mu\) and variance \(\sigma^ 2\) and g be a function on \({\mathbb{R}}\) which is twice continuously differentiable near \(\mu\) and satisfies the conditions \(g(\mu ...
Woodroofe, Michael, Keener, Robert
openaire +2 more sources

