Results 71 to 80 of about 1,466,559 (292)

Beyond single domains: Writing in boundary crossing [PDF]

, 2014
The chapter explains the role of text production in intellectual, cultural, and social mobility in a digital age. Written communication is becoming increasingly important across the domains, where in order to produce text people must cross boundaries ...
Oakey, David, Russell, David
core  

Lighthouse as a transdisciplinary boundary-crossing learning innovation

, 2023
The Lighthouse was a learning activity that offered entrepreneurship pedagogy outside the academic structures of higher education, in a religious context, and among grassroots practitioners.
Woods, Christine, Steve Taylor, Johnston, Mark, Taylor, Steve, Christine Woods, Mark Johnston   +5 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Boundary Crossing Support in Part-Time Higher Professional Education Programs [PDF]

, 2020
As learning societies necessitate continuous education, a growing number of part-time programs are being offered. A key challenge for part-time programs is adequately supporting students in connecting their learning within the program to their work life,
Bronkhorst, Larike H., Arts, Margit, Education and Learning: Development in Interaction, Leerstoel Akkerman   +3 more
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Explicit Bounds for Approximation Rates for Boundary Crossing Probabilities for the Wiener Process [PDF]

We give explicit upper bounds for convergence rates when approximating (both one- and two-sided general curvlinear) boundary crossing probabilities for the Wiener process by similar probabilities for close boundaries (of simpler form for which computing ...
K. Borovkov, Alexander Novikov
core  

Expensive or expansive? Learning the value of boundary crossing in design projects [PDF]

, 2016
Boundary crossing is a strategy as well as a tactic to bridge the gap between different activities in an organization. In design projects, boundary crossing is mainly associated with strategies such as multidisciplinary teams, integrated delivery methods
van Amstel, FMC, Dewulf, Geert P.M.R., Zerjav, V, Dewulf, GPMR, Hartmann, T, Zerjav, Vedran, van der Voort, MC, van Amstel, Frederick, van der Voort, Mascha C., Hartmann, Timo   +9 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source