Results 91 to 100 of about 404,554 (315)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Maximum Principle for Boundary Control Problems Arising in Optimal Investment with Vintage Capital [PDF]

open access: yes
The paper concerns the study of the Pontryagin Maximum Principle for an infinite dimensional and infinite horizon boundary control problem for linear partial differential equations.
Silvia Faggian
core  

Structure of the Turbulent Boundary Layer under Static and Dynamic Impulsive Roughness Perturbation [PDF]

open access: yes, 2013
The zero-pressure gradient turbulent boundary layer at Reynolds numbers (based on momentum thickness) ranging from 2700--4100 was perturbed using an impulsively short patch of two-dimensional, spanwise roughness elements.
Jacobi, Ian
core   +1 more source

Optimal Boundary Control in a Micromixer

open access: yesExamples and Counterexamples
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Manuel Wegmann   +3 more
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Control of shock-induced boundary layer separation at supersonic speeds

open access: yes, 2007
PhDThe results of a systematic experimental investigation into the effects that Sub- Boundary Layer Vortex Generators (SBVGs) have on reducing normal shock-induced turbulent boundary layer separation are presented.
Cohen, Giel S, Cohen, Giel S.
core  

Optimal boundary control of a viscous Cahn-Hilliard system with dynamic boundary condition and double obstacle potentials [PDF]

open access: yes, 2014
In this paper, we investigate optimal boundary control problems for Cahn--Hilliard variational inequalities with a dynamic boundary condition involving double obstacle potentials and the Laplace--Beltrami operator.
Sprekels, Jürgen   +5 more
core   +1 more source

Global Mittag-Leffler Synchronization of Fractional-Order Fuzzy Inertia Neural Networks with Reaction–Diffusion Terms Under Boundary Control

open access: yesFractal and Fractional
This study is devoted to solving the global Mittag-Leffler synchronization problem of fractional-order fuzzy reaction–diffusion inertial neural networks by using boundary control.
Lianyang Hu   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Optimal control of a moving boundary by laser heating in a 2-phase Stefan problem

open access: yes, 2008
The 2-phase heat control problem by a single laser point input is studied and a method of overcoming the moving boundary problem is introduced. This is achieved by applying a sequence of linear time varying control problems which converge to the single ...
Xu, Xu   +3 more
core  

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