Results 121 to 130 of about 10,644,671 (308)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

On the boundary control of a flexible robot arm [PDF]

open access: yesProceedings of the 40th IEEE Conference on Decision and Control (Cat. No.01CH37228), 2002
We consider a flexible robot arm modeled as a single flexible link clamped to a rigid body. We assume that the system performs only planar motion. For this system, we pose two control problems; namely, the orientation and stabilization of the system. We propose a class of controllers to solve these problems.
openaire   +3 more sources

Optimal control of a moving boundary by laser heating in a 2-phase Stefan problem

open access: yes, 2008
The 2-phase heat control problem by a single laser point input is studied and a method of overcoming the moving boundary problem is introduced. This is achieved by applying a sequence of linear time varying control problems which converge to the single ...
Xu, Xu   +3 more
core   +1 more source

Maximum Principle for Boundary Control Problems Arising in Optimal Investment with Vintage Capital [PDF]

open access: yes
The paper concerns the study of the Pontryagin Maximum Principle for an infinite dimensional and infinite horizon boundary control problem for linear partial differential equations.
Silvia Faggian
core  

Series 7: Press releases [PDF]

open access: yes, 1946
Series consists of a number of press releases regarding the upcoming Boundary Centennial ...

core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Inverse Optimality of Regulation Design for Korteweg-De Vries-Burgers Equation

open access: yesIEEE Access
In optimal control, it is often necessary to solve Hamilton-Jacobi-Isaacs (HJI) partial differential equation, but it is not only difficult to solve, sometimes even impossible to solve.
Xiushan Cai, Cong Lin
doaj   +1 more source

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