Results 81 to 90 of about 19,207,286 (312)

Global Mittag-Leffler Synchronization of Fractional-Order Fuzzy Inertia Neural Networks with Reaction–Diffusion Terms Under Boundary Control

open access: yesFractal and Fractional
This study is devoted to solving the global Mittag-Leffler synchronization problem of fractional-order fuzzy reaction–diffusion inertial neural networks by using boundary control.
Lianyang Hu   +5 more
doaj   +1 more source

Mittag-Leffler Stabilization of an Unstable Time Fractional Hyperbolic PDE

open access: yesIEEE Access, 2019
This paper aims to study the Mittag-Leffler stabilization of an unstable time fractional hyperbolic partial differential equation by boundary control and boundary measurement.
Chunwan Lv, Huacheng Zhou, Feiqi Deng
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Optimal control problems for nonlinear parabolic boundary control systems: the Dirichlet boundary condition

open access: yesDifferential and Integral Equations, 1994
A boundary control system described by a semilinear partial differential heat equation is considered. The control is applied through the forced Dirichlet boundary condition. The optimal control problem is that of minimizing a cost functional among all determined admissible controls for which the corresponding solutions satisfy a given target condition.
Fattorini, H. O., Murphy, T.
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Exact boundary controllability for higher order nonlinear Schrodinger equations with constant coefficients

open access: yesElectronic Journal of Differential Equations, 2005
The exact boundary controllability of the higher order nonlinear Schrodinger equation with constant coefficients on a bounded domain with various boundary conditions is studied.
Juan Carlos Ceballos V.   +2 more
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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