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‘They Were Surprised That Such Jobs Even Exist…’ Supporting Students’ Career Awareness During Learning Activities at Museums and Environmental Education Centres

open access: yesSocial Sciences
Many factors influence students’ career awareness and future career choices. Curricula-related learning activities that entail boundary-crossing between formal and nonformal contexts, such as museums and environmental education centres, can also broaden ...
Helene Uppin, Inge Timoštšuk
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Suppression of Magnetopause Reconnection in the Presence of Cold Magnetospheric Plasma

open access: yesEarth and Space Science
The temporal variability of magnetopause reconnection is an important aspect of solar wind magnetosphere coupling. Even under stable solar wind driving, reconnection can be triggered, modulated, or suppressed because of magnetic field and plasma ...
Krishna Khanal, Ying Zou, Gary P. Zank
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Computation of the Survival Probability of Brownian Motion with Drift Subject to an Intermittent Step Barrier

open access: yesAppliedMath
This article provides an exact formula for the survival probability of Brownian motion with drift when the absorbing boundary is defined as an intermittent step barrier, i.e., an alternate sequence of time intervals when the boundary is piecewise ...
Tristan Guillaume
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Boundary Crossing Issues Between Academia, Business and Government [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2005
In this paper issues arising from crossing boundaries between the three worlds of academia, business and government in performing informatics research are explored.
Kay Fielden
doaj  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Translanguaging as Boundary Crossing

open access: yes, 2023
Objectives: 1. Determine attitudes towards translanguaging in the Netherlands; 2. Investigate interactions between non-formal and informal learning settings and the role of translanguaging strategies therein; 3.
Hanneke Baart   +6 more
core   +1 more source

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