Results 71 to 80 of about 1,481,716 (292)

Explicit Bounds for Approximation Rates for Boundary Crossing Probabilities for the Wiener Process [PDF]

We give explicit upper bounds for convergence rates when approximating (both one- and two-sided general curvlinear) boundary crossing probabilities for the Wiener process by similar probabilities for close boundaries (of simpler form for which computing ...
K. Borovkov, Alexander Novikov
core  

Expensive or expansive? Learning the value of boundary crossing in design projects [PDF]

, 2016
Boundary crossing is a strategy as well as a tactic to bridge the gap between different activities in an organization. In design projects, boundary crossing is mainly associated with strategies such as multidisciplinary teams, integrated delivery methods
van Amstel, FMC, Dewulf, Geert P.M.R., Zerjav, V, Dewulf, GPMR, Hartmann, T, Zerjav, Vedran, van der Voort, MC, van Amstel, Frederick, van der Voort, Mascha C., Hartmann, Timo   +9 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Navigating towards interdisciplinarity: a grounded theory exploration of a collaborative SoTL boundary experience

Cogent Education
This study investigates the intricacies of interdisciplinary collaboration within the Scholarship of Teaching and Learning (SoTL), a field characterized by its epistemic and methodological diversity.
Janice Miller-Young, Jillian Seniuk Cicek, Jeff Paul   +2 more
doaj   +1 more source

What’s in a name? Defining interdisciplinary learning within and outside the medical realm

Research and Humanities in Medical Education, 2022
Interdisciplinary learning facilitates communication and collaboration with disciplines from outside the medical realm, as is needed in an increasingly complex healthcare system.
Jessica Oudenampsen, Enny Das, Marjolein van de Pol   +2 more
doaj  

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Beyond disciplines: Strengthening boundary crossing through geography

Geo: Geography and Environment
It is now widely acknowledged by many academics, practitioners and policy‐makers that working across the boundaries of disciplines, sectors, and institutions is vital if we are to effectively address the challenges of sustainability in practice ...
Gary Kass
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

On Crossing Boundaries

Roczniki Nauk Społecznych
The article outlines the issue of crossing boundaries in art, starting with Marcel Duchamp, through conceptualism, and ending with bioart and zoesthetics. The focus was on the conceptual side of this phenomenon, while omitting its social, political and cultural dimensions.
openaire   +3 more sources