Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The boundary element method - a review
Not available.
H. M. Semple
doaj +2 more sources
ANALISA ELASTISITAS DENGAN BOUNDARY ELEMENT
Dalam tulisan ini, analisa elastisitas dengan boundary element method disampaikan. Perumusan-perumusan boundary element method juga diperkeknalkan. Untuk menyelesaikan persamaan yang didapatkan integrasi numerik diterapkan.
Supriyono Supriyono
doaj
A static and dynamic analysis of Kirchhoff plates is presented in this paper. The proposed approach avoids Kirchhoff forces at the plate corners and equivalent shear forces at a plate boundary. Two unknown variables are considered at the boundary element
Michał Jan GUMINIAK
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Stochastic Vibrations of a System of Plates Immersed in Fluid Using a Coupled Boundary Element, Finite Element, and Finite Difference Methods Approach. [PDF]
Guminiak M +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Effects of Infill Plate's Interconnection and Boundary Element Stiffness on Steel Plate Shear Walls' Seismic Performance. [PDF]
Paslar N, Farzampour A.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Boundary Element and Sensitivity Analysis of Anisotropic Thermoelastic Metal and Alloy Discs with Holes. [PDF]
Fahmy MA, Alsulami MO.
europepmc +1 more source

