Results 121 to 130 of about 1,397,215 (290)

Boundary Element Fast Multipole Method for Enhanced Modeling of Neurophysiological Recordings. [PDF]

open access: yesIEEE Trans Biomed Eng, 2021
Makarov SN   +5 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Isogeometric boundary element method for solving 2D multi-media heat conduction problems

open access: yesResults in Applied Mathematics
In this work, we employ the isogeometric boundary element approach to investigate heat transfer mechanisms in various media. We derive and construct integral equations for the interface of different media to address heat transfer issues.
Kunpeng Li, Wei Jiang, Haozhi Li
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Adaptive FE-BE coupling for strongly nonlinear transmission problems with friction II

open access: yes, 2013
This article discusses the well-posedness and error analysis of the coupling of finite and boundary elements for transmission or contact problems in nonlinear elasticity.
Gimperlein, Heiko, Stephan, Ernst P.
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Vibration isolation effects of pile barriers in layered saturated transversely isotropic foundations under moving loads

open access: yesYantu gongcheng xuebao
The vibration isolation effects of pile rows in saturated layered transversely isotropic soils due to moving loads are evaluated using the finite-element-boundary-element coupled method. The finite element matrix equations for the pile are obtained based
YANG Shuai 1, 2, JIA Mincai 1, 2
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

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