Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Inverse estimates for elliptic boundary integral operators and their application to the adaptive coupling of FEM and BEM [PDF]
We prove inverse-type estimates for the four classical boundary integral operators associated with the Laplace operator. These estimates are used to show convergence of an h-adaptive algorithm for the coupling of a finite element method with a boundary ...
Aurada, Markus +5 more
core
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
2D Structural Acoustic Analysis Using the FEM/FMBEM with Different Coupled Element Types
A FEM-BEM coupling approach is used for acoustic fluid-structure interaction analysis. The FEM is used to model the structure and the BEM is used to model the exterior acoustic domain.
Leilei CHEN +3 more
doaj +1 more source
A Computational Model for Nonlinear Biomechanics Problems of FGA Biological Soft Tissues
The principal objective of this work was to develop a semi-implicit hybrid boundary element method (HBEM) to describe the nonlinear fractional biomechanical interactions in functionally graded anisotropic (FGA) soft tissues.
Mohamed Abdelsabour Fahmy
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Investigation of a boundary simulation of continuity using the discrete solid element method
The discrete solid element method is an efficient numerical method that simulates the large deformation, strong material nonlinearity, fracture, and dynamic problems of continuity.
Baochen Zhu, Ruoqiang Feng
doaj +1 more source
A quadtree-polygon-based scaled boundary finite element method for image-based mesoscale fracture modelling in concrete [PDF]
A quadtree-polygon scaled boundary finite element-based approach for image-based modelling of concrete fracture at the mesoscale is developed. Digital images representing the two-phase mesostructure of concrete, which comprises of coarse aggregates and ...
A.A. Saputra +59 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

