Results 51 to 60 of about 121,834 (259)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

COUPLING BOUNDARY ELEMENT METHOD WITH LEVEL SET METHOD TO SOLVE INVERSE PROBLEM

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2017
The boundary element method and the level set method can be used in order to solve the inverse problem for electric field. In this approach the adjoint equation arises in each iteration step.
Tomasz Rymarczyk, Paweł Tchórzewski, Jan Sikora   +2 more
doaj   +1 more source

n-sided polygonal hybrid finite elements involving element boundary integrals only for anisotropic thermal analysis

Archives of Mechanics, 2020
As a combination of the traditional finite element method and boundary element method, the n-sided polygonal hybrid finite element method with fundamental solution kernels, named as HFS-FEM, is thoroughly studied in this work for two-dimensional heat ...
R.F. Cao, X.J. Zhao, W.Q. Lin, H. Wang
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Nonlinear boundary element method and its applications: a review

Cogent Engineering
The Boundary Element Method (BEM) has long been recognized as an efficient numerical technique for the solution of linear boundary value problems, particularly those involving unbounded domains, free-surface effects and radiation conditions. However, its
Kirana Kumara P
doaj   +1 more source

Evolutionary computation in optimization and identification

Computer Assisted Methods in Engineering and Science, 2023
The aim of the paper is to present the application of the evolutionary algorithms to selected optimization and identification problems of mechanical systems. The coupling of evolutionary algorithms with the finite element method and the boundary element
Tadeusz Burczyński, Witold Beluch, Adam Długosz, Wacław Kuś, Marek Nowakowski, Piotr Orantek   +5 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

ANALISA ELASTISITAS DENGAN BOUNDARY ELEMENT

Media Mesin, 2016
Dalam tulisan ini, analisa elastisitas dengan  boundary element method disampaikan. Perumusan-perumusan boundary element method juga diperkeknalkan. Untuk menyelesaikan persamaan yang didapatkan integrasi numerik diterapkan.
Supriyono Supriyono
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source