Results 41 to 50 of about 121,834 (259)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The Global Element Method for Three- Dimensional Potential Problems

open access: yesIEEE Access
This paper presents the Global Element Method (GEM) for solving three-dimensional potential problems. Compared to traditional boundary element methods, this approach offers significant advantages.
Xinrong Li, Chao Zhang, Yaoming Zhang
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Sensitivity analysis of non-uniform rational B-splines–based finite element/boundary element coupling in structural-acoustic design

open access: yesFrontiers in Physics
For the purpose of modeling the acoustic fluid-structure interaction using direct differentiation method and conducting a structural-acoustic sensitivity analysis, a coupling approach based on the finite element method and the fast multipole boundary ...
Yanming Xu, Sen Yang, Sen Yang
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

RETRACTED : Composite parameters analysis with boundary element method

open access: yesJournal of Materials and Engineering Structures, 2019
This article has been retracted at the request of the Editors-in-Chief, according to the Publication Ethics Policy and Publication Malpractice Statement.
Ahmed SAHLI   +2 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

STRUCTURAL SHAPE OPTIMIZATION BY ISOGEOMETRIC BOUNDARY ELEMENT METHOD

open access: yesJixie qiangdu, 2019
In Isogeometric boundary element method(IGA-BEM), Non-Uniform Rational B-Splines(NURBS) which are used for describing the geometric boundary in a computer-aided geometric design(CAGD) are employed as shape functions of Boundary Element Method.
SUN ShaoHui, YIN ShuoHui
doaj  

Application of the Green Element Method to Chemical Engineering Problems

open access: yesJournal of King Saud University: Engineering Sciences, 2004
The novel Green element method (GEM), which applies the singular boundary integral theory (a Fredholm integral equation of the second kind) on each element at a time, is herein implemented on chemical engineering problems.
M.E.E. Abashar
doaj   +1 more source

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