Results 101 to 110 of about 6,521,077 (382)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A feasibility study of using Langley 0.3-m transonic cryogenic tunnel sidewall boundary-layer removal system for heavy gas testing [PDF]

open access: yes
This report presents the results of a preliminary study for using the 0.3-m Transonic Cryogenic Tunnel sidewall boundary-layer removal system with heavy gas sulfur hexafluoride as the test medium.
Balakrishna, S.   +2 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The ISSI international study team on the martian PBL – status report and plan [PDF]

open access: yes, 2008
Dynamical processes in the Martian boundary layer provide the means of communication between surface ice deposits and the free atmosphere, and the means of lifting dust from the surface.
Galperin, B.   +13 more
core  

Vertical distribution of particle-phase dicarboxylic acids, oxoacids and α -dicarbonyls in the urban boundary layer based on the 325 m tower in Beijing [PDF]

open access: gold, 2020
Wanyu Zhao   +13 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Quantitative Decoupling Analysis for Assessing the Meteorological, Emission, and Chemical Influences on Fine Particle Pollution

open access: yesJournal of Advances in Modeling Earth Systems
A comprehensive understanding of meteorological, emission and chemical influences on severe haze is essential for air pollution mitigation. However, the nonlinearity of the atmospheric system greatly hinders this understanding.
Junhua Wang   +9 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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