Results 101 to 110 of about 1,102,249 (248)

Quantitative Decoupling Analysis for Assessing the Meteorological, Emission, and Chemical Influences on Fine Particle Pollution

Journal of Advances in Modeling Earth Systems
A comprehensive understanding of meteorological, emission and chemical influences on severe haze is essential for air pollution mitigation. However, the nonlinearity of the atmospheric system greatly hinders this understanding.
Junhua Wang, Baozhu Ge, Lei Kong, Xueshun Chen, Jie Li, Keding Lu, Yayuan Dong, Hang Su, Zifa Wang, Yuanhang Zhang   +9 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

High-Resolution Remote Sensing of the Gradient Richardson Number in a Megacity Boundary Layer

Remote Sensing
The Gradient Richardson Number (Ri) is an important parameter for appraising the stability and turbulence exchange at the atmospheric boundary layer (ABL). However, high-resolution measurements of Ri profiles are rarely reported, especially in megacities.
Simin Yang, Yongjing Ma, Wenyu Zhang, Xinbing Ren, Kecheng Peng, Masroor Ahmad, Danjie Jia, Dandan Zhao, Lingbin Kong, Yining Ma, Jinyuan Xin   +10 more
doaj   +1 more source

Framing Failures in Wood-Frame Hip Roofs under Extreme Wind Loads

Frontiers in Built Environment, 2018
Wood-frame residential roof failures are among the most common and expensive types of wind damage. Hip roofs are commonly understood to be more resilient during extreme wind in relation to gable roofs.
Sarah A. Stevenson, Gregory A. Kopp, Ayman M. El Ansary   +2 more
doaj   +1 more source

Studies of sidewall boundary layer in the Langley 0.3 meter transonic cryogenic tunnel with and without suction [PDF]

Boundary layer measurements on the sidewalls of the Langley 0.3 Meter Transonic Cryogenic Tunnel were made to determine the effectiveness of the passive boundary layer bleed system over a Reynolds number range from 20 to 200 x 10 to the sixth power per ...
Johnson, C. B., Lawing, P. L., Murthy, A. V., Ray, E. J., Thibodeaux, J. J.   +4 more
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Vortex boundary-layer interactions [PDF]

The interaction of a turbulent boundary layer (on a flat plate) with a strong artificially-generated longitudinal vortex, which may or may not actually enter the boundary layer, was studied.
Bradshaw, P.
core   +3 more sources

On optical imaging through aircraft turbulent boundary layers [PDF]

, 1980
Optical resolution quality as affected by aircraft turbulent boundary layers is analyzed. Wind-tunnel data was analyzed to obtained the variation of boundary layer turbulence scale length and mass density rms fluctuations with Mach number.
Sutton, G. W.
core   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source