Results 51 to 60 of about 1,352,612 (256)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Topology Optimization of Suction Muffler for Noise Attenuation [PDF]

, 2012
A topology optimization method is developed to optimally design suction mufflers in reciprocating compressors. Suction mufflers should be designed for high noise reduction.
Choi, Dong Wook, Lee, Jin Woo
core   +1 more source

Boundary shape identification method for density based topology optimization

Nihon Kikai Gakkai ronbunshu, 2022
Topology optimization is an advanced design method that is used to generate lightweight and high-performance structures by determining the material distribution.
Yoshinori NISHIO, Yang LIU, Nagato ONO
doaj   +1 more source

Topology of the Misner space and its $$g$$ g -boundary [PDF]

General Relativity and Gravitation, 2014
The Misner space is a simplified $2$-dimensional model of the $4$-dimensional Taub-NUT space that reproduces some of its pathological behaviours. In this paper we provide an explicit base of the topology of the complete Misner space $\mathbb{R}^{1,1}/boost$.
Margalef-Bentabol, Juan, Villaseñor, Eduardo J. S.   +1 more
openaire   +4 more sources

The Seiberg-Witten equations on 3-manifolds with boundary [PDF]

, 1999
The Seiberg-Witten equations have proved to be quite powerful in studying smooth 4-manifolds since their landing in 1994. The corresponding Seiberg-Witten theory on closed 3-manifolds can either be obtained by a dimension reduction from the four ...
Yang, Qing
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Infernal and exceptional edge modes: non-Hermitian topology beyond the skin effect

JPhys Materials, 2023
The classification of point gap topology in all local non-Hermitian (NH) symmetry classes has been recently established. However, many entries in the resulting periodic table have only been discussed in a formal setting and still lack a physical ...
M Michael Denner, Titus Neupert, Frank Schindler   +2 more
doaj   +1 more source

Topological boundaries of representations and coideals

Advances in Mathematics
For a locally compact quantum group $\mathbb{G}$, a (left) coideal is a (left) $\mathbb{G}$-invariant von Neumann subalgebra of $L^\infty(\mathbb{G})$. We introduce and analyze various generalizations of amenability and coamenability to coideals of discrete and compact quantum groups.
Anderson-Sackaney, Benjamin, Khosravi, Fatemeh   +1 more
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source