Results 61 to 70 of about 352,298 (333)

Monodomain Liquid Crystals of Two-Dimensional Sheets by Boundary-Free Sheargraphy

open access: yesNano-Micro Letters, 2022
Highlights Monodomain liquid crystals of graphene oxide over 30 cm is realized by boundary-free sheargraphy. The achieved monodomain liquid crystals have bidirectional sheet ordering, exhibiting unique optical, rheological, and conductive properties ...
Min Cao   +15 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Topological grain boundary segregation transitions

open access: yesScience
Engineering the structure of grain boundaries (GBs) by solute segregation is a promising strategy to tailor the properties of polycrystalline materials. Solute segregation triggering phase transitions at GBs has been suggested theoretically to offer different pathways to design interfaces, but an understanding of their intrinsic atomistic nature is ...
Vivek Devulapalli   +4 more
openaire   +4 more sources

Entanglement entropy of topological orders with boundaries [PDF]

open access: yesJournal of High Energy Physics, 2018
Abstract In this paper we explore how non trivial boundary conditions could influence the entanglement entropy in a topological order in 2+1 dimensions. Specifically we consider the special class of topological orders describable by the quantum double.
Chen, Chaoyi   +3 more
openaire   +4 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Invertible Dirac operators and handle attachments on manifolds with boundary

open access: yes, 2014
For spin manifolds with boundary we consider Riemannian metrics which are product near the boundary and are such that the corresponding Dirac operator is invertible when half-infinite cylinders are attached at the boundary.
Adams R. A.   +10 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Extraction of Connected Region Boundary in Multidimensional Images

open access: yesImage Processing On Line, 2014
This paper presents an algorithm to extract the boundary of a connected region(s) using classical topology definitions. From a given adjacency definition, the proposed method is able to extract the boundary of an object in a generic way, independently of
David Coeurjolly   +2 more
doaj   +1 more source

TOPOLOGY DESIGN AND MODAL ANALYSIS OF A BRACKET VIA FEA [PDF]

open access: yesApplied Engineering Letters, 2019
In this study, topology optimization of a jet engine bracket which was proposed from GE Aviation challenge for improving the brackets is presented using finite element analysis (FEA).
Erdi Gülbahçe   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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