Results 61 to 70 of about 15,810,034 (284)

Clusterization and phase diagram of the bimodal Kuramoto model with bounded confidence

open access: yes, 2022
Inspired by the Deffuant and Hegselmann-Krause models of opinion dynamics, we extend the Kuramoto model to account for confidence bounds, i.e., vanishing interactions between pairs of oscillators when their phases differ by more than a certain value.
Jacquod, Philippe   +2 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Bounded-confidence models of opinion dynamics with neighborhood effects

open access: yesPhysical Review E
18 pages, extensively ...
Sanjukta Krishnagopal, Mason A. Porter
openaire   +3 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Repulsive Bounded-Confidence Model of Opinion Dynamics in Polarized Communities

open access: yes, 2023
Collective opinions affect civic participation, governance, and societal norms. Due to the influence of opinion dynamics, many models of their formation and evolution have been developed.
Feng, Michelle, Kann, Claudia
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

A polarization opinion model inspired by bounded confidence communications

open access: yesJournal of the Franklin Institute
We present an opinion model founded upon the principles of the bounded confidence interaction among agents. Our objective is to explain the polarization effects inherent to vector-valued opinions. The evolutionary process adheres to the rule where each agent aspires to increase polarization through communication with a single friend during each ...
Jacek Cyranka, Piotr B. Mucha
openaire   +5 more sources

SMT-based bounded model checking for embedded ANSI-C software

open access: yes, 2012
Propositional bounded model checking has been applied successfully to verify embedded software but remains limited by increasing propositional formula sizes and the loss of high-level information during the translation preventing potential optimizations ...
Joao Marques-Silva   +9 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Robust Clustering in Generalized Bounded Confidence Models [PDF]

open access: yesJournal of Artificial Societies and Social Simulation, 2016
Bounded confidence models add a critical theoretical ingredient to the explanation of opinion clustering, opinion polarisation, and the persistence of opinion diversity, assuming that individuals are only influenced by others who are sufficiently similar and neglect actors with too different views.
Takasumi Kurahashi-Nakamura   +2 more
openaire   +3 more sources

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