Results 51 to 60 of about 1,238,535 (282)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

A universal bound on the variations of bounded convex functions [PDF]

open access: yes, 2015
Given a convex set $C$ in a real vector space $E$ and two points $x,y\in C$, we investivate which are the possible values for the variation $f(y)-f(x)$, where $f:C\longrightarrow [m,M]$ is a bounded convex function. We then rewrite the bounds in terms of
Kwon, Joon
core  

On a question of Eremenko concerning escaping components of entire functions

open access: yes, 2006
Let f be an entire function with a bounded set of singular values, and suppose furthermore that the postsingular set of f is bounded. We show that every component of the escaping set I(f) is unbounded.
Rempe, Lasse
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Integral Representation of Functions of Bounded Variation

open access: yesJournal of Mathematics, 2019
Functions of bounded variations form important transition between absolute continuous and singular functions. With Bainov’s introduction of impulsive differential equations having solutions of bounded variation, this class of functions had eventually ...
Z. Lipcsey   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Slice Holomorphic Functions in the Unit Ball Having a Bounded L-Index in Direction

open access: yesAxioms, 2020
Let b∈Cn\{0} be a fixed direction. We consider slice holomorphic functions of several complex variables in the unit ball, i.e., we study functions that are analytic in the intersection of every slice {z0+tb:t∈C} with the unit ball Bn={z∈C:|z|:=|z|12 ...
Andriy Bandura   +2 more
doaj   +1 more source

AN EXISTENCE AND UNIQUENESS OF THE SOLUTION OF SEMILINEAR MONOTONE ELLIPTIC EQUATION WITH THE DATA IN STUMMEL CLASSES

open access: yesBarekeng, 2023
Let  be a bounded open subset of , ,  be a function in Stummel classes , where , and be a semilinear monotone elliptic equation, where  is  symmetric matrix, elliptic, bounded, and  is non decreasing and Lipschitz. By proving a weighted estimation for
Nicky Kurnia Tumalun
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Parameterized inequalities based on three times differentiable functions

open access: yesBoundary Value Problems
This paper presents a general identity including two real parameters for three times differentiable functions. By using this equality, we prove several inequalities by using diverse function classes such as convex function, bounded function, Lipschitzian
Bouharket Benaissa   +2 more
doaj   +1 more source

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