Results 71 to 80 of about 1,241,136 (285)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analytic functions in the unit ball of bounded L-index in joint variables and of bounded 𝐿-index in direction: a connection between these classes

open access: yesDemonstratio Mathematica, 2019
We give negative answer to the question of Bordulyak and Sheremeta for more general classes of entire functions than in the original formulation: Does index boundedness in joint variables for an entire function F imply index boundedness in the variable ...
Bandura Andriy, Skaskiv Oleh
doaj   +1 more source

Uniqueness of Bounded Harmonic Functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1989
We prove the following theorem: A bounded harmonic function is identically zero if it tends to zero at a certain rate along a set of radii of positive measure. In particular, this uniqueness theorem does not require that the function in question have smooth boundary values or restricted derivatives.
Marvin Ortel, Walter Schneider
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On the Nemytskii Operator in the Space of Functions of Bounded (p, 2, α)-Variation with Respect to the Weight Function

open access: yesDemonstratio Mathematica, 2014
In this paper, we consider the Nemytskii operator (Hf)(t) = h(t, f(t)), generated by a given function h. It is shown that if H is globally Lipschitzian and maps the space of functions of bounded (p,2,α)-variation (with respect to a weight function α ...
Aziz Wadie
doaj   +1 more source

Polynomial Threshold Functions, AC^0 Functions and Spectral Norms [PDF]

open access: yes, 1990
The class of polynomial-threshold functions is studied using harmonic analysis, and the results are used to derive lower bounds related to AC^0 functions.
Bruck, Jehoshua, Smolensky, Roman
core  

Generation of subordinated holomorphic semigroups via Yosida's theorem

open access: yes, 2014
Using functional calculi theory, we obtain several estimates for $\|\psi(A)g(A)\|$, where $\psi$ is a Bernstein function, $g$ is a bounded completely monotone function and $-A$ is the generator of a holomorphic $C_0$-semigroup on a Banach space, bounded ...
Gomilko, Alexander, Tomilov, Yuri
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy