Results 91 to 100 of about 45,775 (301)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Sign changing solutions of the Hardy–Sobolev–Maz'ya equation
In this article we will study the existence, multiplicity and Morse index of sign changing solutions for the Hardy–Sobolev–Maz'ya (HSM) equation in bounded domain and involving critical growth.
Ganguly Debdip
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Cesàro Summable Sequence Spaces over the Non-Newtonian Complex Field
The spaces ω0p, ωp, and ω∞p can be considered the sets of all sequences that are strongly summable to zero, strongly summable, and bounded, by the Cesàro method of order 1 with index p.
Uğur Kadak
doaj +1 more source
By constructing a special cone and using fixed point index theory, this paper investigates the existence of positive solutions of singular superlinear coupled integral boundary value problems for differential systems $$\left\{ \begin{array}{ll} -x''(t ...
Yujun Cui, Jingxian Sun
doaj +1 more source
Functions of Exponential Type are Differences of Functions of Bounded Index
The notion of entire function of Bounded Index is by now well established. It may be stated as follows.An entire function f(z) is said to be of Bounded Index if for some fixed sfor all n and all z. (See [1], [2].)
Shantilal N. Shah
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
On the Ritt order of a certain class of functions
The authors introduce the notions of Ritt order and lower order to functions defined by the series ∑1∞fn(s)exp(−λns) where (λn) is a D-sequence and fn(s) are entire functions of bounded index.
R. Parvatham, J. Thangamani
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
QUALITATIVE AND QUANTITATIVE ESTIMATES FOR MINIMAL HYPERSURFACES WITH BOUNDED INDEX AND AREA [PDF]
We prove qualitative estimates on the total curvature of closed minimal hypersurfaces in closed Riemannian manifolds in terms of their index and area, restricting to the case where the hypersurface has dimension less than seven.
Buzano, Reto +4 more
core +1 more source

