Results 81 to 90 of about 4,511,459 (292)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Measuring the Socio-Economic Bipolarization Phenomenon [PDF]
The present paper emphasizes the differences between the Gini concentration coefficient [13] and a new bipolarization index proposed by [20], [21]. In practice, the Gini index is applied frequently to determine the poverty degree of the persons of a ...
Stefananescu, Stefan
core
New bounds for the acyclic chromatic index
Discrete Mathematics, 2016 An edge coloring of a graph $G$ is called an acyclic edge coloring if it is proper and every cycle in $G$ contains edges of at least three different colors. The least number of colors needed for an acyclic edge coloring of $G$ is called the acyclic chromatic index of $G$ and is denoted by $a'(G)$.
openaire +4 more sources
Some Bounds for the Kirchhoff Index of Graphs [PDF]
Abstract and Applied Analysis, 2014 The resistance distance between two vertices of a connected graphGis defined as the effective resistance between them in the corresponding electrical network constructed fromGby replacing each edge ofGwith a unit resistor. The Kirchhoff index ofGis the sum of resistance distances between all pairs of vertices.
openaire +3 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A note on multivalence of functions of bounded index
, 1973 This paper examines the relationship between the concept of bounded index and the radius of univalence, respectively p p -valence, of entire functions and their derivatives at arbitrary points in the plane.
Gerd H. Fricke
core +1 more source
Contamination and comprehensive risk assessment of heavy metals in Liangtan River, Chongqing, China
Chemical Speciation & Bioavailability, 2016 Distribution and fraction of heavy metals (Pb, Cr, Zn, and Mn) in water and sediment in Liangtan River, Chongqing was analyzed using the atomic absorption spectrometry method.
Lei Wang +4 more
doaj +1 more source
Where is Bounded Rationality From?
Annals of Business Administrative Science, 2015 “Bounded rationality” has become such a key concept that the mere mention of the name “Simon” calls this phrase to mind. Nonetheless, this phrase does not appear in the original text of Administrative Behavior (Simon, 1947, 1957, 1976, 1997). In spite of
Nobuo TAKAHASHI
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source