Results 81 to 90 of about 42,373 (259)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Bounds for the modified eccentric connectivity index

open access: yesCoRR, 2014
The modified eccentric connectivity index of a graph is defined as the sum of the products of eccentricity with the total degree of neighboring vertices, over all vertices of the graph. This is a generalization of eccentric connectivity index. In this paper, we derive some upper and lower bounds for the modified eccentric connectivity index in terms of
Nilanjan De   +2 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Unified Loadability Quality Factor (ULQF): A bounded and interpretable voltage stability index

open access: yesInternational Journal of Electrical Power & Energy Systems
Voltage stability assessment remains a critical challenge in evolving power networks, which are increasingly influenced by load variability, renewable energy integration, and distributed energy resources.
Manuel Jaramillo   +2 more
doaj   +1 more source

A discrete Stochastic Korovkin theorem

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
In this article we give a sufficient condition for the pointwise −− in the first mean Korovkin property on B0(P), the space of stochastic processes with real state space and countable index set Γ and bounded first moments.
George A. Anastassiou
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Composition of entire function and analytic functions in the unit ball with a vanished gradient

open access: yesМатематичні Студії
The composition $H(z)=f(\Phi(z))$ is studied, where $f$ is an entire function of a single complex variable and $\Phi$ is an analytic function in the $n$-dimensional unit ball with a vanished gradient. We found conditions by the function $\Phi$ providing
A. I. Bandura, T. M. Salo, O. B. Skaskiv
doaj   +1 more source

Nonfragile Robust Finite-Time L2-L∞ Controller Design for a Class of Uncertain Lipschitz Nonlinear Systems with Time-Delays

open access: yesAbstract and Applied Analysis, 2013
The nonfragile robust finite-time L2-L∞ control problem for a class of nonlinear uncertain systems with uncertainties and time-delays is considered.
Jun Song, Shuping He
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Modelling Financial Risk in the South African Stock Market: An Application of the Generalised Extreme Value Distribution (GEVD)

open access: yesEconometric Research in Finance
This study analyses the return characteristics of the South African Industrial Index (J520) and South African Financial Index (J580) using the Generalized Extreme Value Distribution (GEVD) to estimate return levels, Value-at-Risk (VaR) and Expected ...
Owen Jakata, Delson Chikobvu
doaj   +1 more source

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