Results 71 to 80 of about 45,775 (301)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Time Dependent Bounded Recall Strategies Are Enough to Play the Discounted Repeated Prisoners' Dilemma [PDF]
We show that for any discount factor, there is a natural number $M$ such that all subgame perfect equilibrium outcomes of the discounted repeated prisoners' dilemma can be obtained by subgame perfect equilibrium strategies with the following property ...
Mehmet Barlo, Guilherme Carmona
core +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Математичні СтудіїThis article is a continuation of the research on the concept of an analytic function of a bounded $\mathbf{L}$-index, conducted during 2019-2025 in the articles A. Bandura, T. Salo and O.
A. I. Bandura +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
PI-Algebras Generated by Nilpotent Elements of Bounded Index
, 1997 LetRbe an associative algebra over a fieldFof positive characteristicp. We address the following problem: ifRis generated by nilpotent elements with bounded index, under what conditions can we conclude thatRitself is nil of bounded index?
Riley, David M.
core +1 more source
Lower bounds for Estrada index and Laplacian Estrada index
Applied Mathematics Letters, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hamidreza Bamdad +2 more
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Contamination and comprehensive risk assessment of heavy metals in Liangtan River, Chongqing, China
Chemical Speciation & Bioavailability, 2016 Distribution and fraction of heavy metals (Pb, Cr, Zn, and Mn) in water and sediment in Liangtan River, Chongqing was analyzed using the atomic absorption spectrometry method.
Lei Wang +4 more
doaj +1 more source
Improving upper bounds for the distinguishing index
Ars Mathematica Contemporanea, 2017 Summary: The distinguishing index of a graph \(G\), denoted by \(D^\prime(G)\), is the least number of colours in an edge colouring of \(G\) not preserved by any non-trivial automorphism. We characterize all connected graphs \(G\) with \(D^\prime(G)\geq \Delta(G)\).
openaire +4 more sources