Results 121 to 130 of about 6,452,940 (353)

Generalized Numerical Index of Function Algebras

open access: yesJournal of Function Spaces, 2019
Let X be a complex Banach space and Cb(Ω:X) be the Banach space of all bounded continuous functions from a Hausdorff space Ω to X, equipped with sup norm.
Han Ju Lee
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Entire Functions of Bounded L-Index: Its Zeros and Behavior of Partial Logarithmic Derivatives

open access: yes, 2017
In this paper, we obtain new sufficient conditions of boundedness of -index in joint variables for entire function in functions. They give an estimate of maximum modulus of an entire function by its minimum modulus on a skeleton in a polydisc and ...
Andriy Ivanovych Bandura, O. Skaskiv
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A bounded index test for robust heterogeneous welfare comparisons. [PDF]

open access: yes
Fleurbaey, Hagneré and Trannoy (2003) develop a bounded dominance test to make robust welfare comparisons, which is intermediate between Ebert’s (1999) cardinal dominance criterion –generalized Lorenz dominance applied to household incomes, divided and ...
Decoster, André, Ooghe, Erwin
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Criteria for selecting resin matrices for improved composite strength [PDF]

open access: yes
Area under matrix of typical stress-strain diagram bounded by one percent strain is good index for priority assessment of matrix contribution to composite strength.
Chamis, C. C.   +2 more
core   +2 more sources

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