Results 121 to 130 of about 45,775 (301)

A bounded index test for robust heterogeneous welfare comparisons

, 2005
Fleurbaey, Hagneré and Trannoy (2003) develop a bounded dominance test to make robust welfare comparisons, which is intermediate between Ebert’s (1999) cardinal dominance criterion –generalized Lorenz dominance applied to household incomes, divided and ...
Decoster, André, Ooghe, Erwin
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Mostar index and bounded maximum degree

Discrete Optimization
Došlić et al. defined the Mostar index of a graph $G$ as $Mo(G)=\sum\limits_{uv\in E(G)}|n_G(u,v)-n_G(v,u)|$, where, for an edge $uv$ of $G$, the term $n_G(u,v)$ denotes the number of vertices of $G$ that have a smaller distance in $G$ to $u$ than to $v$.
Michael A. Henning, Johannes Pardey, Dieter Rautenbach, Florian Werner 0003   +3 more
openaire   +3 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Measuring the Socio-Economic Bipolarization Phenomenon

The present paper emphasizes the differences between the Gini concentration coefficient [13] and a new bipolarization index proposed by [20], [21]. In practice, the Gini index is applied frequently to determine the poverty degree of the persons of a ...
Stefananescu, Stefan
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Supersloppy Readings: Indexicals as Bound Descriptions

Journal of Semantics, 2019
AbstractThis article explores understudied dependent readings in (English) ellipsis and focus constructions and their theoretical consequences. The main focus is on “supersloppy” readings of person indexicals in VP-ellipsis, in which you can be bound by I and vice versa.
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Nonlinear maps preserving Drazin invertible operators of bounded index

, 2020
Given an integer n ≥1, we provide a complete description of all bijective bicontinuous maps, on the algebra of all bounded linear operators acting on an innite-dimensional complex or real Banach space, that preserve the difference of Drazin invertible ...
Oudghiri, Mourad, Souilah, Khalid
core  

Weakly q-Convex Domains and Bounded q-Subharmonic Exhaustion Functions

, 2022
We generalize the Diederich-Fornaess index to bounded weakly q-convex domains with bounded q-subharmonic exhaustion functions. Sufficient conditions for this generalized Diederich-Fornæss index to have a given lower bound are proved.
Foss, Emily
core