Poland and Polin: New Interpretations in Polish-Jewish Studies. Ed. Irena Grudzińska-Gross and Iwa Nawrocki . Eastern European Culture, Politics and Societies, Vol. 10, eds. Irena Grudzińska-Gross and Andrzej W. Tymowski . Frankfurt am Main: Peter Lang GmBH, 2016. xvi, 229 pp. Appendix. Notes. Index. Illustrations. $60.95, hard bound. [PDF]
Piotr Wróbel
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Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
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Index Formulas for Countably φ−Set Contraction
In this paper, we study the index formulas for a class of bounded linear operators, namely ϕ−set contractions, acting on a Banach space and we discuss some application of this class of operators to the theory of bifurcation points.
H. Salahifard, S. M. Vaezpour
doaj +2 more sources
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
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Magaziny “Berezka”: Paradoksy potrebleniia v pozdnem SSSR. By Anna Ivanova. Moscow: Novoe literaturnoe obozrenie, 2017. 298 pp. Notes. Bibliography. Index. Illustrations. Plates. Photographs. RUB 379, hard bound. [PDF]
Sergei I. Zhuk
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Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
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The Index of Invariant Subspaces of Bounded below Operators on Banach Spaces
George Chailos
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ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
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HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
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