Results 51 to 60 of about 70,010 (263)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Weighted bounded mean oscillation applied to backward stochastic differential equations [PDF]

open access: yesStochastic Processes and their Applications, 2020
We deduce conditional $L_p$-estimates for the variation of a solution of a BSDE. Both quadratic and sub-quadratic types of BSDEs are considered, and using the theory of weighted bounded mean oscillation we deduce new tail estimates for the solution $(Y,Z)$ on subintervals of $[0,T]$.
Ylinen, Juha, Geiss, Stefan
openaire   +5 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Making proofs without Modus Ponens: An introduction to the combinatorics and complexity of cut elimination [PDF]

open access: yes, 1996
This paper is intended to provide an introduction to cut elimination which is accessible to a broad mathematical audience. Gentzen's cut elimination theorem is not as well known as it deserves to be, and it is tied to a lot of interesting mathematical ...
Carbone, Alessandra, Semmes, S.
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Equivalence of norms on finite linear combinations of atoms

open access: yes, 2010
Let M be a space of homogeneous type and denote by F^\infty_{cont}(M) the space of finite linear combinations of continuous (1,\infty)-atoms. In this note we give a simple function theoretic proof of the equivalence on F^\infty_{cont}(M) of the H^1-norm ...
Mauceri, G., Meda, S.
core   +1 more source

Current Tracking Adaptive Control of Brushless DC Motors

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
In this paper, the current tracking for Brushless Direct Current motors is approached considering uncertainty in the parameters of the motor's model. An adaptive control scheme to compensate electrical parameters uncertainty is proposed without requiring any knowledge of the mechanical parameters.
Fernanda Ramos‐García   +3 more
wiley   +1 more source

Logarithmic mean oscillation on the polydisc, endpoint results for multi-parameter paraproducts, and commutators on BMO

open access: yes, 2012
We study boundedness properties of a class of multiparameter paraproducts on the dual space of the dyadic Hardy space H_d^1(T^N), the dyadic product BMO space BMO_d(T^N). For this, we introduce a notion of logarithmic mean oscillation on the polydisc. We
Pott, Sandra, Sehba, Benoit
core   +1 more source

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