Results 41 to 50 of about 3,800 (242)
Intangible Capital, 2019 Purpose: This paper analyses the foundations of trust in a context of bounded rationality to arrive to the conclusion that for trust to be necessary is because individuals are bounded rational.
Natàlia Cugueró, Josep M. Rosanas
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Medicine as a Science of Design
Azafea: Revista de Filosofía, 2022 There is a long dispute in the philosophy of medicine between those who consider medicine as an applied science and those who defend that is an art. We defend an alternative: medicine is a science of design. Doing this allows us to introduce prescriptive
Ana Cuevas Badallo +1 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Transparency in competitive tendering: The dominancy of bounded rationality
Cogent Business & Management, 2022 In an era of intense false impressions, cognitive limitations and imperfect information, where critical challenge is the management of procedural relationships among public procurement partners, it is essential to exploit and identify sources associated ...
Hamisi K. Sama
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Two-Sided Matching with Bounded Rationality: A Stochastic Framework for Personnel Selection
MathematicsPersonnel selection represents a two-sided matching problem in which firms compete for qualified candidates by designing job-offer packages. While traditional models assume fully rational agents, real-world decision-makers often face bounded rationality ...
Saeed Najafi-Zangeneh +2 more
doaj +1 more source
The bounded rationality of the educational choices
Encyclopaideia, 2015 Nowadays, models adopted by the educational systems met with rigidities and doctrinal axioms that are limiting the efficacy of the interventions. This is due to a reduced capacity of adaptability to the reality.
Simone Digennaro, Antonio Borgogni
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source