Results 61 to 70 of about 15,568 (347)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Study on the Selection of Pharmaceutical E-Commerce Platform Considering Bounded Rationality under Probabilistic Hesitant Fuzzy Environment [PDF]
, 2023 Zixue Guo, Sijia Liu
openalex +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Rationality Levels in a Heterogeneous Dynamic Price Game
AxiomsThe Bertrand game is one of the basic game models in modern microeconomics. In some behavior experiments with game theory, it was shown that agents have different bounded rationality levels.
Min Guo, Qiqing Song
doaj +1 more source
, 2021 There is little doubt that one of Simon’s key contributions throughout his scientific career - if not the main one - was rooting the notion of bounded rationality in cognitive psychology (Simon, 1976).
Gallese V. +3 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A Survey on Entropy and Economic Behaviour
Entropy, 2020 Entropy plays a significant role in the study of games and economic behaviour in several ways. A decision maker faced with an n-fold repetition of a decision-making problem needs to apply strategies that become increasingly complex as n increases.
Ziv Hellman, Ron Peretz
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Aspects of Bounded Rationality in Resource Use [PDF]
Ovidius University Annals: Economic Sciences SeriesRationality in economics, corroborated with the idea that human action, essentially economic life, cannot be consumed far from rationality, as it has been analyzed by all economic thinkers, is neither inscribed in the sphere of purity nor is it whole.
Marius-Mihai Rusu
doaj
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source