Results 81 to 90 of about 398,756 (302)
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Simonian bounded rationality hypothesis and the expectation formation mechanism [PDF]
. In the 1980s and at beginning of the 1990s the debate on expectation formation mechanism was dominated by the rational expectation hypothesis. Later on, more interest was directed towards alternative approaches to expectations analysis, mainly based on
Kowalski, Tadeusz
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Testing Bounded Rationality Against Full Rationality in Job Changing Behavior [PDF]
In this paper I question the hypothesis of full rationality in the context of job changing behaviour, via simple econometric explorations on microdata drawn from WHIP (Worker Histories Italian Panel).
Bruno Contini
core
Parametric management of economic actor behaviour under bounded rationality
The article explores parametric management of economic entity production volume within framework of weak and strong hypothesis of bounded rationality. The concept of parametric management with the example of economic entity behavior modeling under the ...
A. YU. Obydenov
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Extending the Bounded Rationality Model: The Distributed Cognition Approach [PDF]
The way Simon, and the major part of the scholars, presented and used bounded rationality directly refers to human computational capabilities (or “brute-force”).
Secchi Davide, Bardone Emanuele
core
Bounded Epistemic Rationality and Norms of Inquiry
Epistemology has recently taken a zetetic turn: a shift in emphasis from the study of norms of belief to norms of inquiry. In this paper, I argue that a non-ideal approach to zetetic normativity can provide norms of inquiry for bounded, psychologically ...
Nastja Tomat
doaj +1 more source
SOME PSYCHOLOGICAL CAUSES OF THE FINANCIAL CRISIS [PDF]
Besides the numerous effects that the financial crisis of 2007 has produced over the entire global economy, its onset has reopened fundamental discussions on the methodology of the economic science.
Paula-Elena DIACON
doaj
The recognition heuristic: A decade of research
The recognition heuristic exploits the basic psychological capacity for recognition in order to make inferences about unknown quantities in the world.
Gerd Gigerenzer +4 more
doaj +1 more source

