Results 81 to 90 of about 477,215 (294)
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Bounded Rationality, Disinformation, and Infodemic in COVID-19 Times [PDF]
Psicologia: Teoria e PesquisaInfodemic is defined by excessive content of different qualities associated with a specific subject and has relevant consequences. The COVID-19 pandemic is unprecedented, exacerbating the search for information and creating some risks, including not ...
Antonio Roazzi +5 more
doaj +1 more source
The Simonian bounded rationality hypothesis and the expectation formation mechanism [PDF]
. In the 1980s and at beginning of the 1990s the debate on expectation formation mechanism was dominated by the rational expectation hypothesis. Later on, more interest was directed towards alternative approaches to expectations analysis, mainly based on
Kowalski, Tadeusz
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Testing Bounded Rationality Against Full Rationality in Job Changing Behavior [PDF]
In this paper I question the hypothesis of full rationality in the context of job changing behaviour, via simple econometric explorations on microdata drawn from WHIP (Worker Histories Italian Panel).
Bruno Contini
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Bounded Epistemic Rationality and Norms of Inquiry
Ars & HumanitasEpistemology has recently taken a zetetic turn: a shift in emphasis from the study of norms of belief to norms of inquiry. In this paper, I argue that a non-ideal approach to zetetic normativity can provide norms of inquiry for bounded, psychologically ...
Nastja Tomat
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Bounded Rationality in the Economics of Organization Present Use and (Some) Future Possibilities [PDF]
The way in which bounded rationality enters contemporary organizational economics theorizing is examined. It is argued that, as it is being used, bounded rationality is neither necessary nor sufficient for producing the results of organizational ...
Nicolai J. Foss
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Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Parametric management of economic actor behaviour under bounded rationality
Стратегические решения и риск-менеджмент, 2017 The article explores parametric management of economic entity production volume within framework of weak and strong hypothesis of bounded rationality. The concept of parametric management with the example of economic entity behavior modeling under the ...
A. YU. Obydenov
doaj +1 more source