Results 31 to 40 of about 3,723,489 (302)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Modeling and Optimizing the System Reliability Using Bounded Geometric Programming Approach
Mathematics, 2022 The geometric programming problem (GPP) is a beneficial mathematical programming problem for modeling and optimizing nonlinear optimization problems in various engineering fields.
Shafiq Ahmad +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
SMT-Based Bounded Model Checking for Embedded ANSI-C Software
, 2009 Propositional bounded model checking has been applied successfully to verify embedded software but is limited by the increasing propositional formula size and the loss of structure during the translation. These limitations can be reduced by encoding word-
Cordeiro, Lucas +5 more
core +3 more sources
Approximation of a singular boundary value problem for a linear differential equation
Қарағанды университетінің хабаршысы. Математика сериясыThis paper addresses the approximation of a bounded (on the entire real axis) solution of a linear ordinary differential equation, where the matrix approaches zero as t →∓∞ and the right-hand side is bounded with a weight. We construct regular two-point
R. Uteshova, Y. Kokotova
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Testing hereditary properties of nonexpanding bounded-degree graphs [PDF]
, 2007 We study graph properties that are testable for bounded-degree graphs in time independent of the input size. Our goal is to distinguish between graphs having a predetermined graph property and graphs that are far from every graph having that property. It
Christian Sohler +5 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source