Results 101 to 110 of about 56,141 (357)

On the boundedness of topological categories [PDF]

open access: yesManuscripta Mathematica, 1974
Let K be a complete and cocomplete category with a given proper (E,M)-factorization. K is called well-bounded if K is moreover bounded with a generator and cowellpowered with respect to the given factorization. Freyd-Kelly proved the following theorem about well-bounded categories: Let K be a well-bounded category and let Γ be a class of cylinders in ...
openaire   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Verification of Computing Grids with Special Edge Conditions by Infinite Petri Nets

open access: yesМоделирование и анализ информационных систем, 2015
A technique of the computing grid verification using invariants of infinite Petri nets was presented. Models of square grid structures in the form of parametric Petri nets for such edge conditions as connection of edges and truncated devices were ...
D. A. Zaitsev
doaj   +1 more source

The molecular characterization of anisotropic Herz-type Hardy spaces with two variable exponents

open access: yesOpen Mathematics, 2020
In this article, the authors establish the characterizations of a class of anisotropic Herz-type Hardy spaces with two variable exponents associated with a non-isotropic dilation on ℝn{{\mathbb{R}}}^{n} in terms of molecular decompositions.
Guo Qingdong, Wang Wenhua
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

On Rado's Boundedness Conjecture

open access: yesJournal of Combinatorial Theory, Series A, 2006
AbstractWe prove that Rado's Boundedness Conjecture from Richard Rado's 1933 famous dissertation Studien zur Kombinatorik is true if it is true for homogeneous equations. We then prove the first nontrivial case of Rado's Boundedness Conjecture: if a1, a2, and a3 are integers, and if for every 24-coloring of the positive integers (or even the nonzero ...
Daniel J. Kleitman, Jacob Fox
openaire   +2 more sources

Continuability and boundedness of solutions to nonlinear second-order differential equations

open access: yesElectronic Journal of Differential Equations, 2010
Continuability, boundedness, and monotonicity of solutions for a class of second-order nonlinear differential equations are discussed. It is proved that all solutions are eventually monotonic and can be extended to infinity under some natural ...
Lianwen Wang, Rhonda McKee, Larysa Usyk
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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