Results 131 to 140 of about 56,141 (357)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri   +2 more
wiley   +1 more source

On the boundedness of Dunkl multipliers

open access: yesStudia Mathematica
20 ...
Mukherjee, Suman, Thangavelu, Sundaram
openaire   +2 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Liapunov functions and boundedness

open access: yesJournal of Mathematical Analysis and Applications, 1977
AbstractIn this paper we give conditions under which one can conclude that all solutions of a differential equation are bounded when there is a Liapunov function which is not radially unbounded. The problem of Lurie and the Liénard equation are given as examples.
openaire   +2 more sources

Boundedness of Bessel–Riesz Operator in Variable Lebesgue Measure Spaces

open access: yesMathematics
In this manuscript, we establish the boundedness of the Bessel–Riesz operator Iα,γf in variable Lebesgue spaces Lp(·). We prove that Iα,γf is bounded from Lp(·) to Lp(·) and from Lp(·) to Lq(·).
Muhammad Nasir   +3 more
doaj   +1 more source

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