Results 181 to 190 of about 187,605 (363)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Dwell Times Reveal Effects of Abstract Event Type on Attention Allocation. [PDF]

Cogn Sci
Yuen J, Lee SH, Papafragou A.
europepmc   +1 more source

Boundedness from H 1 to L 1 of Riesz transforms on a Lie group of exponential growth [PDF]

, 2008
Peter Sjögren, Maria Vallarino
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Mathematical modeling of carbon dioxide emissions with GDP linkage: sensitivity analysis and optimal control strategy. [PDF]

Carbon Balance Manag
Liu H, Gangji Z, Wei Y, Ye J, Ma G.
europepmc   +1 more source

Boundedness of a Kantorovich type of the Szász-Mirakjan Operator [PDF]

Oki Neswan, ‎Denny Ivanal Hakim, Ifronika, Wono Setya-Budhi   +3 more
openalex   +1 more source

A nonlinear attraction-repulsion Keller–Segel model with double sublinear absorptions: criteria toward boundedness

, 2023
Yutaro Chiyo, Silvia Frassu, Giuseppe Viglialoro   +2 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Prominence-guided link prediction in fuzzy robotic networks. [PDF]

Sci Rep
Jeyakumar DJ, Rajkumar V, Peter TPD, Gomathi N.   +3 more
europepmc   +1 more source