Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Robust observer-sliding mode composite control for mechanical systems under uncertain disturbances. [PDF]
Li Q, Hu Y, Fang X.
europepmc +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Photo-thermoelastic diffusive waves with microconcentration in quantum-modified semiconductors. [PDF]
Mohammed AM +4 more
europepmc +1 more source
Comparable Stocks, Boundedly Rational Stock Markets and IPO Entry Rates [PDF]
Jay Chok, Jifeng Qian
openalex
On the Boundedness of Random Solutions of Nonlinear Stochastic Integral Equations
Hiroshi Onose
openalex +2 more sources
Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley +1 more source
The Lie Group Basis of Neuronal Membrane Architecture: Why the Hodgkin-Huxley Equations Take Their Form. [PDF]
Melendy RF, Blue DH.
europepmc +1 more source
On the boundedness character of third-order rational difference equations
Eugene P. Quinn
openalex +2 more sources

