Results 61 to 70 of about 142,415 (276)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
This paper is devoted to the proof of boundedness of bilinear smooth square functions. Moreover, we deduce boundedness of some bilinear pseudo-differential operators associated with symbols belonging to a subclass of $BS^0_{0,0}$.Comment: 27 ...
Bernicot, Frederic, Shrivastava, Saurabh
core +1 more source
Boundedness of the twisted paraproduct
We prove \mathrm{L}^p estimates for a two-dimensional bilinear operator of paraproduct type. This result answers a question posed by Demeter and Thiele.
openaire +5 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Rigidity and flexibility of surface groups [PDF]
The aim of this work is the °exibility of the hyperbolic surfaces. The results are about °exibility and geometrical boundedness. Bers are stated the universal property for all hyperbolic surface of ¯nite area where introduced the constant of boundedness.
Grácio, Clara, Ramos, José Sousa
core
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Boundedness and exponential convergence of a chemotaxis model for tumor invasion
We revisit the following chemotaxis system modeling tumor invasion \begin{equation*} \begin{cases} u_t=\Delta u-\nabla \cdot(u\nabla v),& x\in\Omega, t>0,\\ v_t=\Delta v+wz,& x\in\Omega, t>0,\\ w_t=-wz,& x\in\Omega, t>0,\\ z_t=\Delta z-z+u, & x\in\Omega,
Jin, Haiyang, Xiang, Tian
core +1 more source
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source