Results 71 to 80 of about 142,415 (276)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
This paper is withdrawn because the results in the paper are included in a paper to be published in Mathematical and Computer ...
openaire +2 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
On the global attractivity and the periodic character of a recursive sequence [PDF]
In this paper we investigate the global convergence result, boundedness, and periodicity of solutions of the recursive sequence \[x_{n+1} = ax_n + \frac{bx_{n-1}+cx_{n+2}}{dx_{n-1}+ex_{n+2}}, \quad n=0,1,\ldots,\] where the parameters \(a\), \(b\), \(c\),
E. M. Elsayed
doaj +1 more source
Supposing that α>0,let g be holomorphic functions in the unit ball B and µ(r) be a normal function on [0,1). Some questions of extended Cesàro operators are studied from µ-Bloch spaces to Zygmund type spaces in the unit ball. By the methods of functional
ZHAOYanhui(赵艳辉)
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos+3 more
wiley +1 more source
On the boundedness operator [PDF]
This paper is a continuation of the study of the boundedness operator δ. By determination of the congruences (that is, collapsings) of the smallest lattice containing δ and closed under application of δ, a nev classification of all topological spaces is obtained according to boundedness criteria.
openaire +2 more sources
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
The boundedness of orthonormal polynomials on certain curves of the fourth degree [PDF]
Dunham Jackson
openalex +2 more sources