Results 81 to 90 of about 17,219 (295)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Boundedness in a quasilinear two-species chemotaxis system with consumption of chemoattractant

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
This paper deals with a two-species chemotaxis system \begin{equation*} \begin{cases} u_t=\nabla\cdot(D_1(u)\nabla u)-\nabla\cdot(u\chi_1(w)\nabla w)+\mu_1 u(1-u-a_1v),\quad &x\in \Omega,\quad t>0,\\ v_t=\nabla\cdot(D_2(v)\nabla v)-\nabla\cdot(v\chi_2(w)\
Jing Zhang   +3 more
doaj   +1 more source

Boundedness in Asymmetric Oscillations

open access: yesJournal of Mathematical Analysis and Applications, 1999
The equation \(x''+ ax^+- bx^-= f(t)\) is studied where \(f(t)\) is a \(2\pi\)-periodic function, \(a\) and \(b\) are positive constants such that \(a\neq b\). It is shown that under some assumptions, all solutions to the equation are bounded, more precisely, if \(x(t)\) is a solution to the equation, then it is defined for all \(t\in \mathbb{R}\), and
openaire   +3 more sources

Substitution and χ -boundedness

open access: yesJournal of Combinatorial Theory, Series B, 2013
A class $\mathcal{G}$ of graphs is said to be {\em $\chi$-bounded} if there is a function $f:\mathbb{N} \rightarrow \mathbb{R}$ such that for all $G \in \mathcal{G}$ and all induced subgraphs $H$ of $G$, $\chi(H) \leq f(\omega(H))$. In this paper, we show that if $\mathcal{G}$ is a $\chi$-bounded class, then so is the closure of $\mathcal{G}$ under any
Chudnovsky, Maria   +3 more
openaire   +3 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Existence of Solutions for a Coupled Hadamard Fractional System of Integral Equations in Local Generalized Morrey Spaces

open access: yesAxioms
This paper introduces a new measure of non-compactness within a bounded domain of RN in the generalized Morrey space. This measure is used to establish the existence of solutions for a coupled Hadamard fractional system of integral equations in ...
Asra Hadadfard   +2 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

A note on the existence of Psi-bounded solutions for a system of differential equations on R

open access: yesElectronic Journal of Differential Equations, 2008
We prove a necessary and sufficient condition for the existence of Psi-bounded solutions of a linear nonhomogeneous system of ordinary differential equations on R.
Aurel Diamandescu
doaj  

Mathematical study of polycystic ovarian syndrome disease including medication treatment mechanism for infertility in women

open access: yesAIMS Public Health
Among women of reproductive age, PCOS (polycystic ovarian syndrome) is one of the most prevalent endocrine illnesses. In addition to decreasing female fertility, this condition raises the risk of cardiovascular disease, diabetes, dyslipidemia, obesity ...
Maryam Batool   +3 more
doaj   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

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