Results 161 to 170 of about 311,946 (315)
Explicit Bounds on Volterra Type Integral Inequalities
, 2015 [[abstract]]In this paper explicit bounds on some volterra type integral inequalities and their discrete analogues are established.
B. G. Pachpatte
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Bounds on the bound \eta ^3He system
, 2004 Comment: 5 pp, 3 ...
Sibirtsev, A. +3 more
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Efficiency bounds for estimating linear functionals of nonparametric regression models with endogenous regressors [PDF]
The main objective of this paper is to derive the efficiency bounds for estimating certain linear functionals of an unknown structural function when the latter is not itself a conditional expectation.
Thomas A. Severini, Gautam Tripathi
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Bounds on Quantiles in the Presence of Full and Partial Item Nonresponse
Microeconomic surveys are usually subject to the problem of item nonresponse, typically associated with variables like income and wealth, where confidentiality and/or lack of accurate information can affect the response behavior of the individual. Follow
Melenberg, B. +2 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Some Upper Bounds for the Product p₁p₂ · · · pn
, 2005 In this note, using refined Mandl’s inequality, Robin’s inequality and a refinement of the AGM inequality, we find some upper bounds for the product p₁p₂ ...
Hassani, Mehdi
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source