Results 51 to 60 of about 286,804 (242)
Mathematics, 2020 In this paper, our objective is to apply a new approach to establish bounds of sums of left and right proportional fractional integrals of a general type and obtain some related inequalities. From the obtained results, we deduce some new inequalities for
Gauhar Rahman +3 more
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Graphs of bounded cliquewidth are polynomially $χ$-bounded [PDF]
Advances in Combinatorics, 2020 We prove that if $\mathcal{C}$ is a hereditary class of graphs that is polynomially $\chi$-bounded, then the class of graphs that admit decompositions into pieces belonging to $\mathcal{C}$ along cuts of bounded rank is also polynomially $\chi$-bounded.
Marthe Bonamy, Michal Pilipczuk
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Letter of Intent: To Be Bound or Not to Be Bound, that Is the Question
European Review of Private Law, 2022 The letter of intent is a broadly used tool in different negotiations throughout the entire world. The legal implications of these documents however aren’t always clear. Depending on ‘the content of the letter of intent as a whole, in combination with the factual circumstances’, a letter can be solely morally binding, establish some juridically binding
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Exploring new upper and lower bounds for the $A_{\alpha}$-energy of graphs [PDF]
Categories and General Algebraic Structures with ApplicationsLet $G$ be a graph on $n$ vertices and $m$ edges. For $\alpha \in [0,1]$, the $A_{\alpha}$-matrix of $G$ is defined as $A_{\alpha}(G) = \alpha D(G) + (1- \alpha) A(G)$, where $A(G)$ is the adjacency matrix and $D(G)$ is the degree diagonal matrix of $G$.
Mainak Basunia, Pratima Panigrahi
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Theory of bounded groups and their bounded cohomology [PDF]
Pacific Journal of Mathematics, 1988 Bounded cohomology H can be defined for groups and for topological spaces. Recent work has shown that \(H^ *_ b(M)\) of a topological space M depends only on \(\pi _ 1(M)\). In this paper we consider a new concept - a bounded group - and thereby expand the definition of bounded cohomology.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source