Results 71 to 80 of about 1,414,908 (321)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Improving bounds on packing densities of 4-point permutations
, 2018 We consolidate what is currently known about packing densities of 4-point permutations and in the process improve the lower bounds for the packing densities of 1324 and 1342.
Sliacan, Jakub, Stromquist, Walter
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
AIMS Mathematics, 2021 In this paper, optimal bounds for the sine and hyperbolic tangent means by arithmetic and centroidal means in exponential type are established using the monotone form of L'Hospital's rule and the criterion for the monotonicity of the quotient of power ...
Ling Zhu, Branko Malešević
doaj +1 more source
Gravitationally Bound Monopoles [PDF]
Physical Review Letters, 2001 Physical Review ...
Hartmann, Betti +2 more
openaire +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A new refinement of Jensen’s inequality with applications in information theory
Open Mathematics, 2020 In this paper, we present a new refinement of Jensen’s inequality with applications in information theory. The refinement of Jensen’s inequality is obtained based on the general functional in the work of Popescu et al.
Xiao Lei, Lu Guoxiang
doaj +1 more source
Improved Error Bounds Based on Worst Likely Assignments
, 2015 Error bounds based on worst likely assignments use permutation tests to validate classifiers. Worst likely assignments can produce effective bounds even for data sets with 100 or fewer training examples.
Bax, Eric
core +1 more source
International Journal of Foundations of Computer Science, 2011 The Parikh finite word automaton model (PA) was introduced and studied by Klaedtke and Rueß. Here, we present some expressiveness properties of a restriction of the deterministic affine PA recently introduced, and use them as a tool to show that the bounded languages recognized by PA are the same as those recognized by deterministic PA. Moreover, this
Michaël Cadilhac +2 more
openaire +3 more sources