Results 41 to 50 of about 1,051,377 (117)

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. [PDF]

open access: yes, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín   +15 more
core   +2 more sources

A Case of Illness Following a Bite by a Male Lone Star Tick (Amblyomma americanum Linnaeus) Infected With Ehrlichia sp. and Rickettsia amblyommatis in Connecticut, United States

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
A case of local lymphadenopathy and a flu‐like illness in a man, following a bite by a male lone star tick infected with Ehrlichia sp. and Rickettsia amblyommatis. ABSTRACT The lone star tick (Amblyomma americanum Linnaeus) is a species commonly found in the southeastern U.S., but in recent years its populations have expanded northward, resulting in an
Noelle Khalil   +4 more
wiley   +1 more source

Pest categorisation of Spodoptera litura

open access: yesEFSA Journal, Volume 17, Issue 7, July 2019., 2019
Abstract The EFSA Panel on Plant Health (PLHP) performed a pest categorisation of Spodoptera litura (Lepidoptera: Noctuidae) for the EU. S. litura is widely distributed across South and East Asia and Oceania. It is established in tropical and subtropical regions where there are no, or few, frost days each year.
EFSA Panel on Plant Health (PLH)   +21 more
wiley   +1 more source

The Role of Glial Cell Senescence in Alzheimer's Disease

open access: yesJournal of Neurochemistry, Volume 169, Issue 3, March 2025.
This review explores the role of glial cell senescence in Alzheimer's disease (ad), highlighting its contribution to neurodegeneration. Glial cells, including astrocytes, oligodendrocytes, and microglia, undergo senescence with aging, leading to chronic inflammation, impaired neuroprotection, and exacerbation of amyloid‐beta and tau pathology ...
Fadhl Alshaebi   +2 more
wiley   +1 more source

Virus demyelination [PDF]

open access: yes, 2003
A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
core   +1 more source

Novel Thogotovirus Associated with Febrile Illness and Death, United States, 2014

open access: yesEmerging Infectious Diseases, 2015
A previously healthy man from eastern Kansas, USA, sought medical care in late spring because of a history of tick bite, fever, and fatigue. The patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness.
Olga I. Kosoy   +6 more
doaj   +1 more source

Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein.

open access: yesPLoS Pathogens, 2020
Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent ...
Jonas Fuchs   +3 more
doaj   +1 more source

JAK Inhibitors for Treatment of VEXAS Syndrome: A Systematic Review of 186 Cases

open access: yesDermatology Research and Practice, Volume 2025, Issue 1, 2025.
Objectives: Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic (VEXAS) syndrome is an autoinflammatory disease with a wide spectrum of manifestations and no standard treatment. Janus kinase inhibitors (JAK‐I) are small‐molecule drugs that affect many molecular pathways.
Saeed Bahramian   +10 more
wiley   +1 more source

EHA2021 Virtual Congress Abstract Book

open access: yes, 2021
HemaSphere, Volume 5, Issue S2, June 2021.
wiley   +1 more source

Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection [PDF]

open access: yes, 2007
Background. CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C.
Paul Klenerman   +175 more
core   +2 more sources

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