This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
Correction: Ban-Cucerzan et al. Bovine Mastitis Therapy at a Crossroads: Pharmacokinetic Barriers, Biofilms, Antimicrobial Resistance, and Emerging Solutions. <i>Pharmaceuticals</i> 2026, <i>19</i>, 175. [PDF]
Ban-Cucerzan A +5 more
europepmc +1 more source
Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging
This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee +5 more
wiley +1 more source
Prolactin and 17β-Estradiol Are Epigenetic Regulators That Modify the Effector Response of Bovine Macrophages During <i>Staphylococcus aureus</i> Challenge. [PDF]
Barajas-Mendiola MA +4 more
europepmc +1 more source
Micro‐injection laser‐assisted bioprinting enables ultrafast and precise patterning of small endothelial cell spheroids by injecting a highly concentrated single‐cell suspension into GelMA/ColMA hydrogels. In co‐culture with fibroblasts, controlled pre‐vasculogenic network formation is obtained at microscale resolution.
Charles Handschin +9 more
wiley +1 more source
Profiles and roles of N6-methyladenosine modification in bovine oocyte maturation. [PDF]
Han T +9 more
europepmc +1 more source
Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
Free Fatty Acids Induce Endoplasmic Reticulum Stress-Mediated Apoptosis of Macrophages in Dairy Cows with Ketosis. [PDF]
Jia H +11 more
europepmc +1 more source
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim +6 more
wiley +1 more source

