Results 41 to 50 of about 12,329 (115)

Microbiological Profile of the Upper and Lower Respiratory Tract of Suckling and Weaned Dairy Calves with Acute Respiratory Disease

open access: yesVeterinary Sciences
Bovine respiratory disease (BRD) is a significant global health issue in cattle farming, leading to substantial economic losses. This study analyzed the microbiological profiles of BRD outbreaks in nine dairy cattle herds in southern Brazil.
Alice Fernandes Alfieri   +3 more
doaj   +1 more source

Varicella‐Zoster Virus‐Specific Cell‐Mediated Immune Response Kinetics and Latent Viral Load Depending on Aging

open access: yesJournal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Herpes zoster (HZ), an infection caused by varicella‐zoster virus (VZV) reactivation, results from an age‐related decline in VZV‐specific cell‐mediated immunity (CMI). Digital droplet PCR (ddPCR) precisely quantifies latent VZV DNA in the blood, a potential biomarker of subclinical viral reactivation and its association with HZ risk.
Hyo‐Ju Son   +5 more
wiley   +1 more source

Designing a highly antigenic multi epitope subunit vaccine against Bovine alpha herpes virus 2 targeting glycoprotein B and H: A reverse vaccinology approach

open access: yesMedicine in Omics
Bovine alphaherpesvirus 2 (BoHV-2), a major pathogen in cattle, belongs to the Herpesviridae family. In this work, we designed a vaccine against BoHV-2 using its envelope glycoprotein B (gB) and glycoprotein H.
Ali Khan   +5 more
doaj   +1 more source

Opinion and report of the French Agency for Food, Environmental and Occupational Health & Safety (ANSES) on the assessment of the impact of fox population dynamics on public health

open access: yesFood Risk Assess Europe, Volume 3, Issue 2, April 2025.
ABSTRACT The Red Fox (Vulpes vulpes) can be hunted as a game species. It may also be listed as a “species likely to cause damage” (ESOD – the acronym in French), for public health reasons among others. Conversely, benefits linked to the presence of foxes are also put forward, such as the predation of rodents carrying zoonotic agents.
Emmanuelle Gilot‐Fromont   +97 more
wiley   +1 more source

Genetic and Biological Characteristics of Gruid Herpesvirus 1 Isolated From Wild Cranes Affected by Inclusion Body Disease of Cranes

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Inclusion body disease of cranes (IBDCs) is fatal in many cases and reportedly caused by a herpes‐like virus labeled as gruid herpesvirus 1 (GrHV‐1). Although GrHV‐1 has been isolated from IBDC‐affected cranes, it has not been genetically classified because its genome has not been partially or fully sequenced.
Kemi Ishikawa   +11 more
wiley   +1 more source

Transplacental Infections Associated with Macavirus in Aborted Bovine Fetuses

open access: yesMicroorganisms
The Macavirus genus, Gammaherpesvirinae subfamily, Herpesviridae family, contains ovine gammaherpesvirus 2 (OvGHV2), the cause of sheep-associated malignant catarrhal fever (SA-MCF).
Flávia Helena Pereira Silva   +9 more
doaj   +1 more source

Pseudorabies Virus UL41 Hijacks IFN Response via JAK/STAT Pathway While Cellular TRIM21 Blocks it Through K48 Ubiquitination

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Pseudorabies virus (PRV), a significant pathogen that infects various animals, including pigs, encodes multiple proteins that participate in host–pathogen interactions. This study investigates the mechanisms by which PRV evades host immune responses, with a particular focus on the role of the UL41 protein and its interactions with host factors.
Xue Li   +7 more
wiley   +1 more source

Celastrol Inhibits Porcine Epidemic Diarrhea Virus Replication by Promoting ROS‐Mediated Apoptosis

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Porcine epidemic diarrhea virus (PEDV) causes acute, highly contagious enteric disease in pigs, leading to severe economic losses, particularly due to high mortality in suckling piglets. Currently, no specific antiviral drugs are available. In this study, we evaluated the anti‐PEDV potential of celastrol, a natural triterpenoid derived from ...
Junhai Zhu   +8 more
wiley   +1 more source

Activation of ZBP1/RIPK3/MLKL‐Dependent Necroptosis by Pseudorabies Virus Restricts Viral Infection in BV2 Microglia Cells

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Pseudorabies (PR) virus (PRV), also known as suid herpesvirus 1, is an alphaherpesvirus that causes huge economic losses in the global swine industry. Necroptosis, a caspase‐independent programmed cell death, has been demonstrated to play an important role in regulating viral infections. Here, we showed that PRV infection triggered receptor‐interacting
Yiyu Liu   +8 more
wiley   +1 more source

RACK1 Associates With STING to Promote Type I Interferon Activation and Inhibit Pseudorabies Virus Infection

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Pseudorabies virus (PRV), the causative agent of Aujeszky’s disease, leads to great economic losses on swine production worldwide. Receptor of activated protein kinase C 1 (RACK1) is initially known as a receptor for protein kinase C, and recent studies indicate that RACK1 can also play critical roles in various virus infections.
Yixuan Li   +9 more
wiley   +1 more source

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